This Group of Research was created 7 years ago. It is directed by Prof. Jean-Françcois Muir. Our collaboration is mainly devoted to investigating time series recorded in various protocole conducted at Universitary Hospital in Rouen. In this context, and supported by ADIR Assistance, two thesis were completed (Linda Achour defended in 2005 and Herinaina Rabarimanantsoa to be defended by December 2, 2008).